Spring 2008 Syllabus (PDF file)
Jan. 21 Intro
Review in basic physiology Ch.
1-3
Jan. 28
Review
in Basic Physiology contd.
Here are the links to the generation of membrane potentials and action potentials
Feb. 4
Hodgkin
Huxley equations
Channels
an Ion selectivity
Ch. 4-7
Here are two papers to read:
Hodgkin
and Huxley (1952) This is the concluding paper in the series
Doyle
et al (1998) This is the Mckinnon paper describing the mechanism of K
channel selective permeability
Also you should look at the following link for the Hodgkin Huxley model HH equation: HH equations
Feb. 11
Intercellular
Communication Ch.
8-9
Feb. 18
Synaptic
mechanisms Ch. 9-10
Feb. 25
Synaptic mechanisms Ch. 9-10 second look
Mar 3
This is the manuscript on which Edaeni will lead the
discussion.
Xue et al 2007
It would also be good to look at this supplementary material
Complexin
Mar. 10
Ionotropic receptors Ch. 11
Here are the slides on this material
Postsynaptic
receptors
Mar. 17
Here is the paper that Ian will be presenting
Vetter et al 2001
Pre-
and post-synaptic metabotropic receptors Ch.
13
Mar. 24 Spring Break
Mar. 31
Pre- and post-synaptic metabotropic receptors Ch. 13
I will present this material: Receptors
April 7
Michael will be presenting a paper from von Gersdorff's lab on cannabinoid
signaling
Kushmerick et al
2004
April 14
Meenakshi will talk about this paper: Patel
et al 2006
Time permitting, I will cover this topic: synaptogenesis
Synaptogenesis Ch. 17,18
Tectum,
Axon growth targeting Ch.
18-20
April 21
Introduction
to Long term plasticity Ch. 19/20
I will talk about implications for synaptic plasticity in the striate cortex: Plasticity
And Stan will talk about ephrins and plasticity in this paper: Armstrong
et al 2006
April 28
Plasticity Ch.
20
For our final meeting Liliana will present this paper: Vecsey
et al 2007
I will cover the following material: LTP
background
May EXAM
